The focus of this issue is on some of the most challenging and controversial surgical procedures that surgeons face and for which there are multiple, unique approaches - webs and contractures, closed reduction of hand fractures, reflex sympathetic dystrophy, and upper limb injury and reconstruction. The editor has chosen to make this volume particularly future-facing through the inclusion of such topics as hand transplantation, outcomes, decision making, research possibilities, and randomized clinical trials. This is an essential reading for hand surgeons in addition to plastic surgeons. <br />